Objective：This study was aimed to investigate factors associated with quality of life (QOL), anxiety and depression in patients with intracranial meningioma. Methods：This is the cross-sectional study of patient with intracranial meningioma in Korea. The European Organisation for Research and Treatment of Cancer QOL Questionnaire 30 and hospital anxiety depression scale were used to assess QOL, anxiety and depressive mood. Multivariate linear regression analysis was used to analyze the related factors. Results：37 patients in total enrolled to be analyzed. In QOL, general health came out low in the patient group with peritumoral edema. Functional scales got lower as patients had higher neurotic tendency and bigger size of tumor. Symptoms scales got higher as patients’ neurotic tendency got higher or as patients had peritumoral edema. Anxiety came out highly related to neurotic tendency and depression found to be related to young age, low agreeableness, high neurotic tendency, and having peritumoral edema. Conclusion：The QOL, anxiety and depression of meningioma patients were both related to their personal character traits and disease-related factors. More attention is needed for the QOL and mental health of intracranial meningioma patients.
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