전기방사를 이용한 히알루론산 멤브레인의 제조 및 금 나노입자 촉매 담체로의 응용

Fabrication of hyaluronic acid membrane using electrospinning method and its application as a catalyst support for gold nanoparticles

In this study, hyaluronic acid (HA) was electro-spun to fabricate nanofibrous membranes for support materials. Because HA is very hygroscopic, it is difficult to obtain enough viscosity to apply electrospinning method. Therefore, we mixed HA with polyethylene oxide (PEO) to obtain proper viscosity and added adipic acid (ADH) to promote cross-linking of PEO/HA during electrospinning. The morphology of PEO/HA membrane was optimized according to PEO/HA concentration ratio and spinning rate. Finally, we fabricated gold-nanoparticle-embedded PEO/HA membranes and their catalyst activities were evaluated in tetramethylbenzidine (TMB) oxidation.