
KCI등재
학술저널
The electroretinographic change by the acute effects of N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine
- Dong Myung Kim Jaeheung Lee
- 대한안과학회
- The Korean Journal of Ophthalmology
- Vol.1 No.1
- 등재여부 : KCI등재
- 1987.06
- 8 - 17 (10 pages)
The electrophysiological effects of N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (NMPTP), a chemical inducer of Parkinsonism in man and monkey, on the pigmented rabbit retina were determined under acute conditions. The amplitude of the b-wave of the rabbit electroretinogram was affected, but both the implirit time and half-amplitude duration of it werenot. The amplitude of the photopic b-wave was increased by 72.9 ± 32.1% 5hours after the intravenous injection of NMPTP (P[t] < 0.05), whereas that of the scotopic b-wave was decreased by 31.2 ± 6.4% 4hours after injection (P[t] < 0.05).
Abstract
INTRODUCTION
MATERIALS AND METHODS
RESULTS
DISCUSSION
REFERENCES