The Significance of Tear Film Break-Up Time in the Diagnosis of Dry Eye Syndrome

The significance of tear film break-up time (BUT) was investigated by analyzing its distribution and reproducibility in 30 normal subjects and 20 dry eye patients. The BUTs* were all above 5 seconds and the reproducibility was 65% in normal subjects. However, those were all below 10 seconds and the reproducibility was 95% in dry eye patients.