학술저널
Antiproliferative Effect of Basic Fibroblast Growth Factor-Saporin Mitotoxin on Keratocytes in Culture
- 대한안과학회
- The Korean Journal of Ophthalmology
- Vol.10 No.1
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1996.061 - 7 (7 pages)
- 0
We evaluated the effect of the conjugate of basic fibroblast growth factor (FGF2) and saporin (FGF2-SAP) on proliferation of cultured keratocytes. Cultured rabbit and human keratocytes were incubated in medium containing 0.01 to 100 nM of chemical conjugate of FGF2 conjugated by disulfide bond to saporin (CCFS1), FGF2 genetically fused to saporin (rFGF2-SAP), FGF2, or saporin for three hours or four days and cell proliferation was quantified four days after the drug treatment.
Abstract
INTRODUCTION
MATERIALS AND METHODS
RESULTS
DISCUSSION
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