
KCI등재
학술저널
Carbon Monoxide Poisoning as an Epigenetic Factor for Leber’s Hereditary Optic Neuropathy
- Jeong Min Hwang Hye Won Park
- 대한안과학회
- The Korean Journal of Ophthalmology
- Vol.10 No.2
- 등재여부 : KCI등재
- 1996.12
- 122 - 123 (2 pages)
A 45-year-old Korean woman visited our hospital complaining of poor vision after carbon monoxide(CO) poisoning. We have confirmed the presence of a point mutation at position 11778 in the ND4 gene of mitochondrial DNA. This case suggests that CO poisoning may precipitate the clinical expression of Leber’s hereditary optic neuropathy(LHON). To our knowledge, this would be the first case report of clinical expression of LHON precipitated by CO poisoning.
Abstract
INTRODUCTION
CASE REPORT
DISCUSSION
REFERENCES