The Inflammatory Potential of Surgical Glove Lubricants: BiosorbⓇ, KeofloⓇ, Calcium Carbonate and Hydrocote™ after Intravitreal Injection

Surgical glove powders have been implicated in serious postoperative foreign body reactions due to contamination of the operative field. Inflammatory responses to glove lubricants or mold release agents have to date been studied to a lesser extent in ocular tissues than other body tissues, although powder contamination of intraocular lenses, with severe postoperative anterior chamber inflammatory responses, have been reported. The object of this study was to grade and quantitate the inflammatory response of surgical glove lubricants, namely BiosorbⓇ, KeofloⓇ, calcium carbonate and Hydrocote™ (a hydrogel polymer film used in powderless gloves), as introduced into the posterior chamber of New Zealand white rabbits.