Fabrication of enzymatic biosensor based on the poly(3-thiophenecarboxylic acid-co-thiophene) polymer as electron-transfer materials
- 한국응용과학기술학회 (구.한국유화학회)
- 한국응용과학기술학회지
- 한국응용과학기술학회지 제36권 제1호
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2019.02269 - 278 (10 pages)
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We fabricated glucose oxidase (GOx)-modified biosensor for detection of glucose by physical immobilization of GOx after electrochemical polymerization of the conductive mixture monomers of the 3-thiophenecarboxylic acid (TCA) and thiophene (Th) onto ITO electrode in this study. We confirmed the successfully fabrication of GOx-modified biosensor via FT-IR spectroscopy, SEM, contact angle, and cyclic voltammetry. The fabricated biosensor has the detection limit of 0.1 μM, the linearity of 0.001-27 mM, and sensitivity of 38.75 mAM-1cm-2, respectively. The fabricated biosensor exhibits high interference effects to dopamine, ascorbic acid, and L-cysteine, respectively. From these results, the fabricated GOx-modified biosensor with long linearity and high sensitivity could be used as glucose sensor in human blood sample.
1. Introduction
2. Experiments
3. Results and Discussion
4. Conclusions
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