티트리, 로즈마리, 멜리사 혼합오일이 창상치유에 미치는 효과

Effect of Mixed Oil of Tea-tree, Rosemary and Melissa on Wound Treatment

The purpose of this study was to evaluate the effect of essential oil on wound healing rate, an epithelial attachment and collagen density in wound induced rat. This study was a 2×3 factorial design. Factors were treatment period (4 day and 8 day) and treatment type [saline (0.9% NaCl), tyrothricin, mixture of tea-tree, rosemary and melissa oil]. The samples were 24 rats with wound and randomly assigned to six groups of four rats per group. The dependent variables such as a wound healing rate, an epithelial attachment and a collagen density were measured. Dependent variables were statistically significant difference by the two treatment periods and the three treatment types (p<.001). There were not statistically significant interactions between treatment periods and treatment type in all dependent variables (p>.05). These findings will be provide bases to develope effective interventions for patients who have wound to manage their wound.