Experience of Comamonas Acidovorans Keratitis with Delayed Onset and Treatment Response in Immunocompromised Cornea

Purpose: To report 2 cases of Comamonas acidovorans keratitis in immunocompromised cornea. Methods: A complete review of the medical records of the two cases of Comamonas acidovorans keratitis. Results: We found some similarities in clinical courses of two cases. Both of them showed development of keratitis during the management with corticosteroids, delayed onset, slow response to antibiotics, and relatively less affected corneal epithelium. Conclusions: Comamonas acidovorans is known as a less virulent organism. However it can cause an indolent infection that responds slowly even to adequate antibiotics therapy in immunocompromised corneas. Korean Journal of Ophthalmology 22(1):49-52, 2008