Subretinal Inflammatory Myofibroblastic Tumor: Clinicopathological Findings

Purpose: To present a case of inflammatory myofibroblastic tumor which was manifested as an idiopathic subretinal mass without underlying pathology. Methods: The subretinal mass was surgically excised and evaluated histopathologically. Fluorescein angiography and optical coherence tomography were performed pre- and post-operatively. Results: The mass was histologically composed of lymphoplasma cell infiltration and fibrous proliferation without microorganisms or malignant cells. Immunohistochemistry for smooth muscle actin revealed myofibroblasts as a major cellular component. Preoperative optical coherent tomography showed that the lesion was contiguous to the retina while inducing foveal detachment. Postoperatively, the fovea was attached with visual recovery, and the subretinal lesion did not recur during the follow up. Conclusions: Inflammatory myofibroblastic tumors may be included in the differential diagnoses of subretinal masses. Korean Journal of Ophthalmology 19(3):235-238, 2005