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학술저널

시타글립틴 유도체의 합성 및 평가

Synthesis and Evaluation of Sitagliptin Analogs

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Abstract Three sitagliptin analogs with propan-2-amine backbone carbon chain and 1,2,3-triazole were synthesized and evaluated for their DPP-4 inhibitory activity against recombinant human DPP-4 enzyme. All the analogs exhibited moderate to strong inhibitory activities.

서 론(Introduction)

실험 방법(Experimental Methods)

결과 및 고찰(Results and Discussion)

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