미세먼지 자극에 의한 저온숙성 선인장 열매 추출물의 생리활성 연구
Study on Bioactivity of Opuntia Ficus-Indica Fruit Extracts fermented Low Temperature by Anti pollutants
- 한국인체미용예술학회
- 한국인체미용예술학회지
- 한국인체미용예술학회지 제21권 제1호
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2020.0361 - 71 (11 pages)
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DOI : 10.18693/jksba.2020.21.1.61
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Air pollutants can trigger various disorders in humans and induce skin aging effects, related cell death, and inflammation. This study demonstrated the effects of low temperature-fermented Opuntia Ficus-Indica Fruit extracts (LTOE) treated total suspended particles (TSP). LTOE induced the expression of pro-inflammatory cytokines such as tumor necrosis factor (TNF)-α, interleukin (IL)-8 without cytotoxicity. To investigate the anti-aging effect, LTOE inhibited the production of matrix metalloproteinase (MMP)-1 (collagenase) more than Opuntia Ficus-Indica Fruit extracts (OE) in TSP-treated Normal human fibroblast cells. This study reports the significant improvement of anti-inflammation and decrease of MMP-1 related to the LTOE, which will be helpful in processing cosmetic ingredients.
Ⅰ. 서론
Ⅱ. 재료 및 방법
Ⅲ. 결과 및 고찰
Ⅳ. 결론
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