새로운 비접촉안압계 HNT-1P의 신뢰성

안압, 중심각막두께, 교정안압에 대한 비교

목적: 새로운 비접촉안압계 HNT-1P의 안압, 중심각막두께, 교정안압을 각각 골드만압평안압계로 측정한 안압, 초음파 각막두께측정계로 측정한 중심각막두께, 이 두 측정치를 이용하여 산출한 교정안압과 비교하여 신뢰도 및 임상적 유용성을 평가하고자 하였다. 대상과 방법: 정상안 또는 녹내장 의증 65명 120안을 대상으로 하였다. HNT-1P로 안압과 중심각막두께를 측정하였으며 이어서 골드만압평안압계로 안압과 초음파 각막두께측정계로 중심각막두께를 측정하였다. 골드만압평안압을 초음파 중심각막두께로 보정하여 교정안압을 산출하였다. HNT-1P와 대조기기들 간의 상관관계를 Pearson 상관분석으로 알아보았으며 일치도를 Bland-Altman plot 분석으로 확인하였다. 결과: HNT-1P와 골드만압평안압계로 측정한 평균 안압 간의 상관계수는 0.964 (p<0.001)였다. HNT-1P와 초음파 각막두께측정계의 측청치 평균중심각막두께 측정치 사이의 상관계수는 0.913 (p<0.001)이었다. HNT-1P와 골드만압평안압계로 확인한 평균 교정안압 측정치 사이는 0.956 (p<0.001)의 상관계수를 보였다. Bland-Altman plot 분석에서 HNT-1P와 각 대조기기 간의 높은 일치도를 보였다. 결론: 새로운 비접촉안압계 HNT-1P는 골드만압평안압계와 초음파 각막두께측정계와 비교하여 높은 일치도 및 신뢰도를 보여 정확한 안압, 중심각막두께, 교정안압을 제공할 수 있을 것으로 보인다.

Purpose: To assess the reliability of a new non-contact tonometer, HNT-1P, by comparing its intraocular pressure (IOP), central corneal thickness (CCT), and corrected IOP (cIOP) measurements with the IOP measured by Goldmann applanation tonometry (GAT), the CCT measured with ultrasound pachymetry (USP), and the cIOP derived from GAT IOP and USP CCT. Methods: A total of 120 eyes of 65 healthy or glaucoma suspects were included in this study. The IOP was measured with the HNT-1P and GAT. The CCT was determined using the HNT-1P and USP. The IOP measured with GAT was corrected according to the CCT measured by USP. The correlations of the measurements obtained with the various instruments were evaluated using Pearson’s correlation coefficient, and the agreement was assessed using Bland-Altman plots. Results: The average IOP measured with the HNT-1P and GAT was 14.8 ± 5.1 mmHg and 15.6 ± 5.2 mmHg, respectively, and the correlation coefficient between the two IOP measurements was 0.964 (p < 0.001). The mean CCT was 553.5 ± 27.4 μm using the HNT-1P and 550.6 ± 26.3 μm using USP, and the correlation coefficient between the two measurements was 0.913 (p < 0.001). The average cIOP was 14.6 ± 5.0 and 13.4 ± 6.5 mmHg according to the HNT-1P and GAT, respectively, and the correlation coefficient between the two corrected measurements was 0.956 (p < 0.001). Bland-Altman plots showed a high degree of agreement between the HNT-1P measurements and those of the other devices. Conclusions: The new non-contact HNT-1P tonometer provided reliable IOP, CCT, and cIOP measurements when compared with GAT and USP. HNT-1P could therefore be used clinically for reliable and accurate measurements of the IOP, CCT, and cIOP.