조혈모세포이식 이후 호흡기 질환을 가진 환자의 호흡물리치료 효과

Effects of Pulmonary Physical Therapy in Patients with Pulmonary Diseases after Hematopoietic Stem Cell Transplantation

Purpose : The purpose of this study was to determine the effect of pulmonary physical therapy in patients with pulmonary disease after hematopoietic stem cell transplantation (HSCT). Methods : The subjects were 25 patients who were diagnosed with pulmonary disease after HSCT. We measured forced vital capacity (FVC), forced expiratory volume in one second (FEV1),FEV1/FVC, r esidual volume ( RV), t otal l ung capacity (TLC), R V/TLC, a nd d iffusion c apacity of c arbon monoxide (DLCO). The data were analyzed using one-way repeated analysis of variance with Bonferonni correction post-hoc. Results : Before pulmonary physical therapy, FVC, FEV1,FEV1/FVCandDLCO were significantly lower than pre-HSCT measurements, and RV and RV/TLC were significantly higher. After pulmonary physical therapy, FVC, FEV1, and DLCO were significantly higher than before pulmonary physical therapy. Conclusion : This study demonstrated that the pulmonary physical therapy was effective in patients with pulmonary disease post-HSCT.