Digoxin Toxicity in Patients with Elevated Digoxin Levels

A retrospective study of 2,709 serum digoxin concentrations assayed at Chonnam National University Hospital during 3-year period was conducted to determine the relationship between digoxin levels of 3.0 ng/ml or higher and digoxin toxicity. Clinical suspicion and creatinine clearance were found to be the significant risk factors for digoxin toxicity. Digoxin toxicity occurred less frequently than previously reported. Appropriately- timed sampling needs to be emphasized.