CA 약침액의 항산화･항염증 효능 및 염증성 사이토카인 억제 효과

Antioxidant, Anti-inflammatory activities and Inhibition Effect on the Inflammtory cytokines of CS Yakchim Fluid

Objectives : This purpose of this study was to analyzed the Biological Activities of CA Yakchim Fluid. Methods : The protein content, glucose content, crude fat content, crude ash content in CA Yachim fluid were analyzed, and DPPH radical scavenging, inhibition of COX-2 activities were investigated. Also TNF-α, IL-6, GAPDH as inflammatory cytokines were measured. Results : The protein, 1.46%, glucose, 0.13%, crude fat 96.18%, crude ash 0.51% in CA Yachim fluid were confirmed. The electron donation ability of CA Yakchim on DPPH WAS 21%. The inhibition of COX-2 activity of CA Yakchim fluid was 68%. The TNF-α, IL-6 were increased in RAW 264.7 treated with LPS, and were decreased in RAW 264.7 pre-treated with CA Yakchim fluid. Conclusions : We conclude that the CA Yakchim fluid has anti-oxidant, anti-inflammatory activities and inhibition effect of the inflammatory cytokines.