HN 약침액에 대한 생리활성분석

Analysis of physioactivities on HN Yakchim

Objectives : The aim of this study is to investigate the contents and physioactivities of HN Yakchim. Methods : In this study, we analyzed the amount of total protein, total glucose, crude fat and crude ash of HN Yakchim. The anti-oxidative effect of HN Yakchim was analyzed by investigating 1,1-diphenyl-2-picryl hydrazyl free radical scavenging activity. To investigate the anti-inflammatory effect of HN Yakchim, cyclooxygenase-2, tumor necrosis factor-α and interleukin-6 were measured. Results : HN Yakchim consists of 0.05% of protein, 0.27% of total glucose, 97.71% of crude fat and 0.49% of crude ash. HN Yakchim showed relatively higher anti-oxidative effect compared to butyl hydroxyanisole. HN Yakchim also showed anti-inflammatory effect by inhibiting cyclooxygenase-2, tumor necrosis factor-α and interleukin-6. Conclusions : HN Yakchim might have anti-oxidant and anti-inflammatory effect. Further investigation including exact mechanisms should be needed.