I 약침액에 대한 생리활성분석

Analysis of physioactivities on I Yakchim

Objectives : The aim of this study is to investigate the contents and physioactivities of I Yakchim. Methods : In this study, we analyzed the amount of total protein, total glucose, crude fat and crude ash of I Yakchim. The anti-oxidative effect of I Yakchim was analyzed by investigating 1,1-diphenyl-2-picryl hydrazyl free radical scavenging activity. To investigate the anti-inflammatory effect of I Yakchim, cyclooxygenase-2, tumor necrosis factor-α and interleukin-6 were measured. Results : I Yakchim consists of 0.06% of protein, 0.31% of total glucose, 97.65% of crude fat and 0.61% of crude ash. I Yakchim showed higher anti-oxidative effect compared to butyl hydroxyanisole. I Yakchim also showed anti-inflammatory effect by inhibiting cyclooxygenase-2, tumor necrosis factor-α and interleukin-6. Conclusions : I Yakchim might have anti-oxidant and anti-inflammatory effect. Further investigation including exact mechanisms should be needed.