OK 약침에 대한 생리활성분석

Analysis of physioactivities on OK Yakchim

Objective : The aim of this study is to investigate the contents and physioactivities of OK yakchim. Methods : In this study, the anti-oxidative effect of OK yakchim was analyzed by investigating 1,1-diphenyl-2-picryl hydrazyl free radical scavenging activity. To investigate the anti-inflammatory effect of OK yakchim, cyclooxygenase-2, tumor necrosis factor-α and interleukin-6 were measured and cell cytotoxicity of OK was also investigated. Results : OK yakchim showed relatively higher anti-oxidative effect compared to butyl hydroxyanisole. OK yakchim also showed anti-inflammatory effect by inhibiting cyclooxygenase-2, tumor necrosis factor-α and interleukin-6. There was no significant cytotoxic effect of OK yakchim. Conclusions : OK yakchim might have anti-oxidant and anti-inflammatory effects. Further investigations including exact mechanisms should be needed.