머위(Petasites japonicus) 추출물의 항산화와 항암활성 효과
The Antioxidant and Anticancer Effects of Butterbur (Petasites japonicus) Extracts
- 서훈석(Hun-Seok Seo) 정봉환(Bong-Hwan Chung) 조용구(Yong-Gu Cho)
- 한국자원식물학회
- 한국자원식물학회지
- 제21권 제4호
- 등재여부 : KCI등재
- 2008.08
- 265 - 269 (5 pages)
The antioxidant activities of the extracts of butterbur (Petasites japonicus) derived from different extraction methods were investigated. SOD (superoxide dismutase)-like activity differed according to the extraction solvents, showing a greater antioxidant effect with ethanol solvent than that of water. Ethanol extracts of butterbur leaves showed higher SOD-like activity of 96.7% than those of water extracts. The contents of polyphenolic compounds were higher in water extracts than those in ethanol extracts. The highest content of polyphenolic compounds was 223mg/g dry weight for butterbur leaves. EDA of butterbur roots was 61.5% in the water extract and EDA in butterbur leaves was 34.9% in the ethanol extract. The anticancer effects with the extracts of butterbur were experimented by fractionations with different solvents. 41.9% of the growth of stomach cancer cells, SNU-719, were inhibited and also 72.7% of the growth of liver cancer cells, Hep3B, were inhibited by the butanol fractions of butterbur, while not affecting the growth of normal cell, DC 2.4.
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