한국인 원발개방각녹내장에서 iStent를 사용한 최소 침습 수술의 효과와 안정성

Efficacy and Safety of iStent Trabecular Microbypass Stent in Open Angle Glaucoma in Korean

Purpose: To evaluate efficacy and safety of the iStent Trabecular Micro-Bypass stent used as the sole procedure in patients with primary open-angle glaucoma (POAG). Methods: Retrospective, consecutive case series involving 12 Korean patients, 12 eyes with POAG that were implanted with 1 iStent trabecular micro-bypass stent. Data were collected preoperatively, and at 1, 3, and 6 months, 12 months, postoperatively. Data included intraocular pressure (IOP), visual acuity test and slit lamp examination. Results: Mean preoperative IOP was 20.6 ± 4.4 mmHg and significantly decreased in 16.3 ± 2.5 mmHg at three months (p < 0.05), in 16.6 ± 3.6 mmHg at 12 months postoperatively (p < 0.05). The mean number of glaucoma medications was 1.83 ± 0.25 preoperatively and 1.58 ± 0.30 (p < 0.05) at 12 months postoperatively. No significant changes in visual acuity were noted. The most common complications comprised mild hyphema in 3 eyes, mild uveitis in 4 eyes and transient IOP spike in 3 eyes on postoperative day 1 and all instances were medically well controlled. Conclusions: The significat IOP reduction after iStent insertion in Korean patients occurred after one week of operation. An IOP reduction from baseline occurred at 12 months after implantation of iStent.