운동강도 차이가 비만 중년여성의 염증반응 지표와 인슐린저항성에 미치는 영향

Effects of Exercise Intensity on Inflammatory Response Index and Insulin Resistance in Obese Middle-aged Women

[PURPOSE] This study was carried out in order to find out the effects of exercise intensity in walking exercise program for 12 weeks on inflammatory response index and insulin resistance in obese middle-aged women. [METHODS] The subjects consisted of the moderate-intensity exercise group(n=10), high-intensity exercise group(n=10), and control exercise group(n=10). Each group had exercised 5 times a week for 12 weeks with the treadmill. The moderate-intensity exercise group had exercised for 50 minutes at 40～60% of heart rate reserve and the high-intensity group had exercised for 40 minutes at 60～80% of heart rate reserve. The changes of obesity index, inflammatory response index and insulin resistance in each group were measured and analyzed at pre- and post- walking exercise program for verifying exercise effectiveness. [RESULTS] The obesity index(weight, % fat and waist circumference), inflammatory response index(TNF--α, IL-6 and hs-CRP) and insulin resistance(blood glucose, insulin and HOMA-IR) of obese middle-aged women after walking exercise program were significantly decreased compared to pre-program, but there was no exercise intensity effects. [CONCLUSIONS] Moderate and high intensity exercise had the positive effects on reduced inflammatory reaction and insulin resistance induced by obesity, but they were not exercise intensity-dependent.