Effects of 2UP-1DOWN Resistance Training Program for Male with Hypertension : Case Report. The Journal of Kinesiology, 2017, 19(1): 63-69. [PURPOSE] The purpose of this case report was to examine the effects of 2UP-1DOWN Resistance Training Program for Adult with Hypertension. [METHODS] The subject was a 40-year-old male who had diagnosed with hy-pertension according to medical exam findings in systolic blood pressure 152mmHg and diastolic blood pressure 100mmHg. 2UP-1DOWN exercise program was performed for 60~70 min/day three times a week for 12-week. 1RM, blood pressure, body composition and Lipids and Glucose Index was measures before and after 12 weeks of exercise completion. [RESULTS] 1RM of leg press (11.43%), leg extension ( 18.75%), leg curl (23.08%), chest press (10.53%), arm curl (25%), cable row (14.29%), and calf raise (11.11%) was increased. Blood pressure of systolic BP (10.53%), and diastolic BP (15%) was decreased. Body composi-tion of body weight (3.45%), muscle mass (2.2%), body mass index (3.44%), and body fat (5.33%) was decreased. Lipids of total cholesterol (18.47%), triglyceride (13.82%), and LDL cholesterol(10.11%) was decreased and HDL cholesterol (17.66%) was increased. Glucose index of fasting blood sugar (5.77%), HbA1C (5.66%) was decreased. [CONCLUSIONS] We demonstrated that 2UP-1DOWN resistance training program improves muscle strength, blood pressure, body composition, lipids and glucose index. Therefore, 2UP-1DOWN resistance training is recommended for male with hypertension.