알레르기 환자 가정에서 생물학적 유해인자에 대한 노출평가

세균, 진균, 집먼지 진드기 알레르겐, 내독소를 대상으로

To assess exposure of allergy patients to a biological environment, measurements were made of levels of airborne bacteria and fungi, house dust endotoxin and mite allergens in homes of 7 allergy patients and 12 healthy families. Concentrations of airborne total bacteria and the ratio of indoor and outdoor concentrations(I/O) in allergy patient s homes were high compared to non-allergy houses. But no significant differences could be shown for the concentration of spores of viable fungi and staphylococcus in indoor air between the homes of allergic patients and healthy families. The results of investigation on house dust mites, Dermatophagoids. farinae were detected in all mattress samples and the levels in the allergy patient`s homes were generally high, with individual measurements exceeding 2 mg/g dust found in 30% samples. In contrast with, Dermatophagoids pteronyssinus were detected in only 60% samples and the concentrations were very low. The levels of endotoxin in dust samples collected from the allergy patient s home mattresses were higher than those of control houses. There was a positive correlation between the endotoxin levels and the house dust mite allergens.