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Apathy: Neurobiology, Assessment and Treatment
- 대한정신약물학회
- Clinical Psychopharmacology and Neuroscience
- Vol.19 No.2
- : SCOPUS, SCIE, KCI등재
- 2021.05
- 181 - 189 (9 pages)
Apathy is a highly prevalent, disabling and treatment resistant syndrome. It is defined as a quantitative reduction of goal-directed activity in comparison to the patient’s previous level of in multiple dimensions including behavior/cognition, emotion and social interaction. It has been described in major depressive disorder, Alzheimer’s disease, frontotemporal dementia, Parkinson’s Disease, cerebrovascular disease, and vascular dementia, among others. This review will address the neuropsychology and associated neurobiological underpinnings of apathy in the above conditions, identify specific methods to assess apathy clinically, and review the literature on managing apathy across these various disorders.
INTRODUCTION
APATHY AND THE REWARD SYSTEM ACROSS PATHOLOGIES
ASSESSMENT OF APATHY
MANAGEMENT OF APATHY
CONCLUSIONS
REFERENCES