안와의 흑색종 방사선치료후 발생한 골육종

Radiation Induced Osteogenic Sarcoma Presenting as a Melanoma in Orbital Area

Introduction Postirradiation osteosarcoma arising after nasopharyngeal cancer is rare and not frequently reported. Case presentation We report irradiation induced osteosarcoma involving the orbit, ethmoid, maxilla and mandible following treatment of melanoma in 45-years-old woman who presented with foul discharge in previous operation site. We present the clinical history, physical findings, imaging studies, and pathologic findings in a patient found to have osteogenic sarcoma of the maxillary sinus and peri-orbit after radiation therapy for a maxillary melanoma. Conclusion Osteogenic sarcoma is a rare and late complication of radiation treatment. Although radiotherapy remains an effective adjuvent treatment in patients with tumor, particularly those with residual or recurrent tumor, potential complications must be acknowledged.