Cholesteatoma of the petrous bone is rare lesion, which may be congenital or acquired in nature, and presents difficulties in its diagnosis and treatment. The availability and the advances in imaging techniques render petrous bone cholesteatoma feasible to diagnose and manage. The removal of the petrous bone cholesteatoma is not easy for the anatomical difficulty of approach. The surgical aim should be complete removal of the cholesteatoma with preservation of existing neuronal function and prevention of CSF leakage. We describe two cases of extensive petrous bone cholesteatoma in which complete removal was accomplished using translabyrinthine approach. One case is supralabyrinthine type petrous cholesteatoma with antero-medial extension and the other is massive labyrinthine type. In both cases, complete removal was possible by using translabyrinthine approach.
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