Objective : Complete protection from CSF(cerebrospinal fluid) leakage after posterior fossa surgerywas difficult, although many variable methods has been performed. Collagen matrix is product toprotect dura defect and prevent CSF leakage. The authors performed collagen matrix underlay graftand identified effectiveness of this technique for CSF sealing.Methods : The authors evaluated 92 posterior fossa surgery used fibrin glue, polyethylene glycol(PEG) sealant, fibrinogen based collagen fleece, collagen matrix between January 2006 andDecember 2015. CSF leakage incidence according to use of variable dura sealing materials wasassessed.Results : CSF leakage occurred 8 cases(8.7%) in 92 posterior fossa surgery. CSF leakage didn’toccur in 42 cases underwent collagen matrix underlay graft. Cases of fibrin glue, polyethyleneglycol(PEG) sealant, fibrinogen based collagen fleece had effect of CSF leakage block, howeverdidn’t have significant difference according to use of this materials.Conclusion : Collagen matrix underlay graft after posterior fossa surgery didn’t have complicationsuch as chemical injury and infection and had effect of CSF sealing.
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