악성수막종의 두개강 외 전이

Malignant meningioma with multiple extracranial metastases: case report and review of literature

Meningioma is the most common benign primary intracranial tumor and rarely metastasizes. Malignant meningioma is a World Health Organization Grade III tumor and constitutes 1 to 3% of all meningioma. The prognosis of the patient of malignant meningioma is very poor because of its frequent recurrence and distant metastasis. There is no guideline concerning the management of extracranial metastasis of meningioma. A 57-old female patient presented with headache and visual disturbance due to huge skull base meningioma. She underwent subtotal mass excision with craniotomy and TSA followed by radiation therapy. However, follow-up brain magnetic resonance imaging (MRI) revealed tumor growing and the patient received additional surgical resection. After 2nd surgery the patient was presented with weakness of both lower extremities. Whole spine MRI demonstrated thoracic spine metastasis compressed spinal cord. Multiple nodules of lung and liver were noticed as well. We report a patient of malignant meningioma with multiple extracranial metastases including review of literature.