Purpose: The population experiencing hair loss has increased given the stress, environmental pollution, and the various cosmetic procedures, and the functional cosmetics market for the scalp hair care is further expanding due to the aging population. However, side effects such as allergies have occurred, and the interest in environmental pollution is rising. Recently, many studies have been conducted to search cosmetic raw materials from natural substances or applied fermentation techniques to the cosmetic manufacturing process. Accordingly, the green coffee beans which are edible and have been used for various pharmacological functions for and by the private sector for long and have secured clinical safety were fermented, then the active ingredients and effectiveness (in vitro) were investigated. Method: After fermenting the green coffee beans which are known to be effective for the scalp hair health by using EM, and preparing a sample using a double fermentation method of enzyme fermentation with malt, active ingredients (caffeine, polyphenol, flavonoid, and sugar) and effectiveness (in vitro, antioxidant activity, anti-inflammatory activity, and the dermal papilla cell growth rate) were verified. Results: As a result of the experiment, the caffeine and sugar content increased during the EM fermentation and enzyme fermentation, and there was no difference discovered according to the enzyme fermentation temper-ature. The total polyphenol and the total flavonoid content decreased during the enzyme fermentation, and enzyme fermentation at 60℃ of EM fermentation solution of green coffee bean extracts demonstrated an excellent rate of anti-inflammatory activity and dermal papilla cell growth. Conclusion: It was verified that the fermented product of the green coffee bean double fermented by using EM and malt has an excellent rate of antioxidant, anti-inflammatory, and dermal papilla cell growth, and hence, it may be applied as a raw material for various cosmetics. In particular, it was verified that it is effective for the scalp and hair health, while the usefulness as a cosmetic material for scalp hair was also verified.