Possible Link between Serotonin and Interleukin 18 on Suicidality in Patients with Acute Coronary Syndrome
Possible Link between Serotonin and Interleukin 18 on Suicidality in Patients with Acute Coronary Syndrome
- 대한정신약물학회
- Clinical Psychopharmacology and Neuroscience
- Vol.21 No.2
- : SCOPUS, SCIE, KCI등재
- 2023.05
- 386 - 390 (5 pages)
Objective: We investigated effects of serum serotonin and interleukin 18 levels on suicidal ideation (SI) at acute and chronic phases of acute coronary syndrome (ACS). Methods: Recent-onset 969 ACS patients were evaluated for serum serotonin and interleukin 18 levels; and SI by the “suicidal thoughts” item of the Montgomery–Åsberg Depression Rating Scale. After 1-year, 711 patients were re-evaluated for SI. Logistic regression models were used adjustment for potential covariates. Results: Associations between serum interleukin 18 and SI at both phases were significant only in the lower serotonin group. Conclusion: By evaluating serum serotonin and interleukin 18 levels, the clinical prediction of SI of ACS may be improved.
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