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Clinical Features and Histopathologic Examination of Lentiginosis Profusa in a Dog

Clinical Features and Histopathologic Examination of Lentiginosis Profusa in a Dog

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An 5-year-old Yorkshire Terrier dog was presented due to a gradually developing hyperpigmented spot at the ventral abdomen, around lips, interdigital space and paws. The skin lesions appeared 2 years ago and gradually increased the numbers. The skin condition was generally dry on presentation, and several hyperpigmented macules and patches were detected. Except for the hyperpigmented skin lesions, other physical examinations and dermatological examination results were non-remarkable. Based on the history and clinical examination results, the genetic dermatological disease, lentigo was highly suspected. Skin biopsy and histopathologic examination were performed to rule out other pigmentary skin disease including tumor. The histopathologic examination revealed epidermal hyperplasia, melanocytic hyperplasia and hyperkeratosis. The dermatologic signs and histopathologic results were compatible with lentiginosis profusa. Canine lentiginosis profusa predominantly occurs in mature dogs and is generally considered a benign condition. While it is primarily a cosmetic concern, it is essential to distinguish it from other hyperpigmentation-related diseases.

1. Introduction

2. Case Report

3. Discussion

4. Conclusion

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