Lipoma is the most common benign tumor in adults, but it is rare in the nasal cavity, paranasal si-nus, and nasal septum. A 44-year-old woman who had a fat autograft during pituitary surgery two months ago visited with a headache and a fetid odor. Although there were no specific findings on her nasal endoscopy, 2.0 cm × 1.5 cm homogenous low-density mass was persisted in the posterior septum and sphenoid sinus on non-contrast computed tomography. Under general anesthesia, we completely removed the mass through endoscopic sinus surgery and postoperative histopathology confirmed it as a fibrolipoma. We report a case of nasal septal fibrolipoma resulting from autologous fat grafted during surgical removal of a pituitary tumor.
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