골절의 절대위험도 평가방법에서 GE Prodigy와 FRAX Tool의 비교분석에 관한 고찰

Studies on the Comparative Analysis Between GE Prodigy and FRAXTM Tool in Absolute Fracture Risk Assessment Tool

Purpose: World Health Organization (WHO) have suggested that an individual’s 10-year absolute fracture risk is more reliable than Bone Mineral Density (BMD) measurement as the predictor of osteoporotic fracture. In 2008, Fracture Risk Assessment Tool (FRAXTM) was developed by WHO to evaluate fracture risk of patients based on individual’s clinical risk factors. The purpose of this study is to offer the comparative analysis of the existing GE prodigy and FRAXTM Tool in Absolute Fracture Risk Assessment Tool. Materials and Methods: 201 women (55±3.5 years) underwent femoral neck BMD measurement using GE Prodigy. The 10-year probability (%) of hip fracture (or a major osteoporosis-related fracture) was estimated using T-scores of GE prodigy and FRAXTM. We made a comparative analysis of these data using SPSS (Ver.12). Results: There was a significant difference statistically between T-score (-0.52±0.97) of GE prodigy and T-score (-1.45±0.81) of FRAXTM (r=0.977, p=0.000). Also, there was a significant difference statistically between a major osteoporosis- related fracture (9.15±3.71) of GE prodigy and a major osteoporosis-related fracture (4.87±1.51) of FRAXTM (r=0.909, p=0.000). Moreover, a statistically significant difference was found in the 10-year probability of hip fracture of GE prodigy (1.56±1.48) and of hip fracture (0.53±0.61) of FRAXTM (r=0.905, p=0.000). Conclusions: There was a significant difference statistically between GE prodigy and FRAXTM Tool in Absolute Fracture Risk Assessment Tool. Especially, T-score, a major osteoporosis-related fracture and the 10-year probability of hip fracture that were estimated using GE prodigy tended to show the higher results than one evaluated by FRAXTM Tool. In conclusion, FRAXTM Tool may provide a better tool. The application of FRAXTM Tool as a fracture predictor remains to be clarified.