⁹⁰Y SIR-Spheres를 사용한 암의 간 전이치료에서 PET 영상획득에 관한 초기연구

Assessment of Acquisition Protocols for Post-Radioembolization Yttrium-90 PET/CT: Initial Study

Purpose: We investigated the quantitative evaluation of PET/CT images for evaluation after treatment in the treatment of liver metastasis of cancer with ⁹⁰YSIR-Sphere. Materials and Methods: Confirmed the correlation between the measured counts was expressed by setting a region of interest from the image and a measure of the dose calibrator to see a correlation diagram of an image in a PET of ⁹⁰Y. A portion uptake coefficients between PET images were acquired for 20 minutes LIST mode in 15 patients treated for liver metastasis of cancer using ⁹⁰Y SIR-Spheres high, intermediate portion, a lower portion, three measuring the coefficient of the region of interest is divided into parts, we studied the conditions for proper image acquisition. Results: Coefficient of sites that set the region of interest of the PET image and the measured counts of ⁹⁰Yappears that there is a correlation diagram statistically, (R²=0.956), correlation diagram from the PET image of ⁹⁰Yis, PET coefficient the coefficients of all regions of interest were increased in proportion to the image acquisition time, partial ROI coefficients of the PET image is higher about 10 minutes on average, about 14 minutes on average, the central portion is lower part 19 minute average in, confirmed the equilibrium of the standard deviation. Conclusion: Using the isotope ⁹⁰Y, it is suitable to obtain a PET image, to obtain the time of proper image, the evaluation of PET/CT images, using the ⁹⁰Y SIR-Spheres and that in the treatment of liver metastases of cancer, it is useful for assessing treatment.