¹⁸F-FDG와 ⁹⁹ᵐTcO₄⁻를 이용한 당일 검사 시 상호 영향에 대한 Phantom 연구

Phantom Study of the Mutual Influences Between ¹⁸F-FDG and ⁹⁹ᵐTcO₄⁻ on the Same Day

Purpose The nuclear medicine examination, there is a difficulty to carry out the inspection of both on the day of residual isotope due to the half-life. In this study, by studying the mutual influence and ¹⁸F-FDG of ⁹⁹ᵐTcO₄⁻, I would like to explain the matters to be considered in the case of performing the same day. Materials and Methods With the NEMA-1994 Phantom, and experiments were performed 3 times. Create a 1: 4 Background ratio HOT and the ⁹⁹ᵐTcO₄⁻ The first experiment: After underwent SPECT in INFINIA (GE Healthcare, MI, USA), and were injected with ¹⁸F-FDG 37 MBq in the Background area, 13 once for 60 minutes under the same conditions was time Scan. Create a 1: 4 Background ratio HOT and the ¹⁸F-FDG second is: The Scan in PET/CT Discovery 600 (GE Healthcare, MI, USA), and 148 MBq after injection ⁹⁹ᵐTcO₄⁻ the Background area, once for 60 minutes, 6 under the same conditions was time Scan. Create a 1: 4 Background ratio HOT and the ¹⁸F-FDG experiments las, increments of 296 MBq and 148 MBq the 1 Bed Scan after ⁹⁹ᵐTcO₄⁻, was 1 Bed Scan under the same conditions. Non BKG area and HOT, I was measured comparing the Total Counts and SNR or CNR. Results Showed a significant difference in the ratio CNR of enforcement during SPECT ¹⁸F-FDG is, (p>0.05). The ⁹⁹ᵐTcO₄⁻ was no significant difference between the SNR ratio of PET / CT at the time of the effective date (p<0.05). I got the results ⁹⁹ᵐTcO₄⁻ that reduce the Total Counts of PET / CT scan. Conclusion If you make a PET / CT scan, may affect the test using the ⁹⁹ᵐTcO₄⁻ up to 12 hours, when it is performed before the ⁹⁹ᵐTcO₄⁻, does not affect the SNR and SUV, PET / CT scan I reduced the detection efficiency. The inspection of day, we'd like to recommend a way to complement the detection efficiency to increase the inspection time of PET / CT in move forward the inspection using the ⁹⁹ᵐTcO₄⁻.