PET 검사 시 Reconstructed data와 Re-sliced data의 표준섭취계수와 Metabolic Tumor Volume의 비교 평가

Evaluation of Standardized Uptake Value and Metabolic Tumor Volume between Reconstructed data and Re-sliced data in PET Study

Purpose SUV is one of the parameters that assist diagnosis in origin, metastasis and staging of cancer. Specially, it is important to compare SUV before and after chemo or radiation therapy to find out effectiveness of treatment. Storing PET data which has no quantitative change is needed for SUV comparison. However, there is a possibility to loss the data in external hard drive or MINIpacs that are managed by department of nuclear medicine. The aim of this study is to evaluate SUV and metabolic tumor volume (MTV) among reconstructed data (R-D) in workstation, R-D and re-sliced data (S-D) in PACS. Materials and Methods Data of 20 patients (aged 60.5±8.3y) underwent ¹⁸F-FDG PET (Biograph truepoint 40, mCT 40, mCT 64, mMR, Siemens) study were analysed. SUVₘₐₓ, SUVₚₑₐₖ and MTV were measured in liver, aorta and tumor after sending R-D in workstation, R-D and S-D in PACS to syngo.via software. Results R-D of workstation and PACS showed the same value as mean SUVₘₐₓ in liver, aorta and tumor were 2.95±0.59, 2.35±0.61, 10.36±6.15 and SUVₚₑₐₖ were 2.70±0.51, 2.07±0.43, 7.67±3.73(p>0.05) respectively. Mean SUVₘₐₓ of S-D in PACS were decreased by 5.18%, 7.22%, 12.11% and SUVₚₑₐₖ 2.61%, 3.63%, 10.07%(p<0.05). Correlation between R-D and S-D were SUVₘₐₓ 0.99, 0.96, 0.99 and SUVₚₑₐₖ 0.99, 0.99, 0.99. And 2SD in balnd-altman analysis were SUVₘₐₓ 0.125, 0.290, 1.864 and SUVₚₑₐₖ 0.053, 0.103, 0.826. MTV of R-D in workstation and PACS show the same value as 14.21±12.72 cm³(p>0.05). MTV in PACS was decreased by 0.12% compared to R-D(p>0.05). Correlation and 2SD between R-D and S-D were 0.99 and 2.243. Conclusion SUVₘₐₓ, SUVₚₑₐₖ, MTV showed the same value in both of R-D in workstation and PACS. However, there was statistically difference in SUVₘₐₓ, SUVₚₑₐₖ of S-D compare to R-D despite of high correlation. It is possible to analyse reliable pre and post SUV if storing R-D in main hospital PACS system.