상세검색
최근 검색어 전체 삭제
다국어입력
즐겨찾기0
Clinical Psychopharmacology and Neuroscience Vol.22 No.2.jpg
SCOPUS 학술저널

Bipolar Disorder, Circadian Rhythm and Clock Genes

Bipolar Disorder, Circadian Rhythm and Clock Genes

DOI : 10.9758/cpn.23.1093

Sleep disturbance and abnormal circadian rhythm might be closely related to bipolar disorder. Several studies involving disturbed sleep/wake cycle, changes in rhythms such as melatonin and cortisol, clock genes, and circadian preference have shown the relationship between bipolar disorder and circadian rhythm. The results differed across different studies. In some studies, a delay in the circadian rhythm was observed in the depressive episode and advanced circadian rhythm was observed during the manic episode. In other studies, a delay in circadian rhythm was observed independent of mood episodes. Accordingly, circadian rhythm disorder was proposed as a trait marker for bipolar disorder. The altered circadian rhythm may represent a pathological mechanism that contributes to the mood episodes. However, a prospective cohort study is needed for further clarification.

BIPOLAR DISORDER AND SLEEP

SLEEP AND CIRCADIAN RHYTHM

CIRCADIAN RHYTHM AND CIRCADIAN PREFERENCE (TYPE)

BIPOLAR ILLNESS AND CIRCADIAN RHYTHM DISORDER

CIRCADIAN RHYTHM AND CLOCK GENES

BIPOLAR DISORDER AND CLOCK GENES

CONCLUSIONS

로딩중