파킨슨병에 대한 추나 치료의 효과 체계적 문헌고찰 및 메타 분석

Effectiveness of Chuna Manipulation Therapy in Treating Parkinson’s Disease: A Systematic Review and Meta-Analysis

Objectives This study was conducted to observe the effects of Chuna manipulation therapy (CMT) in patients with Parkinson’s disease (PD). Methods We performed a comprehensive search of various databases such as MEDLINE(Pubmed), EMBASE, CENTRAL, OASIS, RISS, ScienceOn, and CNKI for randomized controlled trials (RCTs) comparing CMT for PD up to December 05, 2024. Risk of Bias was tested using the Cochrane RoB tool. The data was visualized and presented using Review Manager 5.4.1. Results Among the 10 RCTs, 5 RCTs that reported unified Parkinson’s disease rating and 5 RCTs that reported total effectiveness rate (TER) were included in the meta-analysis. CMT treatment revealed a statistically obvious improvement in UPDRS and TER relative to Western medicine (WM) for Parkinson’s disease. Moreover, when CMT combined with traditional Korean medicine such as acupuncture, pharma- copuncture and herbal medicine were used, statistically significant improvements were observed. Conclusions Most studies have shown that CMT is effective in improving UPDRS and TER in Parkinson's disease. However, the evaluation criteria used to measure the effects of CMT varied across studies, and the duration and methods of Chuna treat- ment differed. Therefore, further researches are needed to standardize these factors and examine the effects more systematically.