하지불안증후군에 대한 추나 치료의 효과 체계적 문헌고찰 및 메타 분석

Effectiveness of Chuna manipulation therapy in Restless Legs Syndrome: A Systematic Review and Meta-Analysis

Objectives This study was conducted to evaluate the effectiveness of chuna ma- nipulation therapy (CMT) for restless legs syndrome(RLS). Methods Through MEDLINE, CENTRAL, EMBASE, KMbase, OASIS, ScienceOn, KISS, CNKI and Wanfang, we conducted comprehensive search for randomized con- trolled trials (RCTs) comparing CMT for RLS up to December 4, 2024. The risk of bias was assessed using the Cochrane risk of bias tool. Results Among the 11 RCTs, 9 RCTs that reported international restless legs syn- drome (IRLS), Pittsburg sleep quality index (PSQI), and total effective rate (TER) were included in the meta-analysis. CMT combined with Korean medicine treatment (KM) showed a statistically significant improvement in IRLS and TER compared with Western medicine (WM) for primary RLS. And CMT combined with KM showed stat- istically significant improvement in IRLS, PSQI, and TER compared to conservative treatment for secondary RLS. Conclusions CMT may be an effective treatment for RLS. However, the quality of evidence of the studies was low and there are some uncertainties due to hetero- geneity in studies. Further studies such as high-quality, well-designed RCTs are needed to support effects of CMT for RLS.