국내 뇌기능 개선제의 현황과 인지기능 관련 영양요소

Overview of Nootropic Agents in South Korea and the Impact of Nutrition on Cognitive Function

With the acceleration of population aging, the prevalence of dementia and the number of patients with cognitive decline have been increasing worldwide, leading to a growing interest in implementing strategies to improve cognitive function and prevent dementia. Current pharmacological treatments of dementia have certain limitations, as they do not fundamentally alter its underlying pathophysiology. Consequently, a growing interest in the use of various nootropic agents and non-pharmacological interventions for the treatment and prevention of dementia has been observed. Commonly used nootropic agents in South Korea, such as choline alfoscerate, ginkgo biloba extract, and nicergoline, as well as specific nutrients like B vitamins, folic acid, and vitamin E, have been shown to positively affect cognitive function. Moreover, healthy dietary patterns, particularly the Mediterranean diet, have shown potential benefits in improving cognitive function and reducing the risk of dementia. These pharmacological and nutritional interventions may serve as potential therapeutic options for preventing and improving cognitive decline in the older adults. However, to better establish their clinical efficacy and safety, further large-scale, long-term randomized controlled trials are needed. Furthermore, with more robust evidence from future studies, these interventions may provide practical support for preventing cognitive impairment.