A 7-year-old spayed female Shih-Tzu was presented with a one-year history of progressive sneezing and nasal discharge, followed by the recent onset of cluster seizures. Magnetic resonance imaging (MRI) revealed a right-sided nasal mass extending through the cribriform plate, with pachymeningeal enhancement suggestive of intracranial invasion. Rhinoscopic examination identified a hypervascular mass within the right nasal cavity, from which biopsy samples were obtained. Histopathological analysis confirmed a diagnosis of nasal carcinoma. The dog was treated with carboplatin-based chemotherapy and oral piroxicam, along with antiepileptic therapy. Follow-up MRI performed seven months after the initial evaluation showed complete resolution of the meningeal enhancement, despite an increase in the size of the nasal mass. Neurological function remained stable, and quality of life was preserved for over 16 months. This case illustrates the feasibility and potential benefit of long-term palliative chemotherapy in small-breed dogs with advanced nasal carcinoma involving intracranial extension.
1. Introduction
2. Case Report
3. Discussion
4. Conclusion
Acknowledgement
Conflict of Interest
Orcid
References
(0)
(0)