노인에 있어서의 칼슘 보충제의 투여가 철분영양상태에 미치는 영향

The effect of calcium supplementation on the iron status of elderly

The present investigation was undertaken to assess the effect of 1,000㎎ of calcium supplementation on the iron status of elderly. The sujects included 66 elderly(male:11, female:55) and devided into calcium supplements group(CG) and placebo group(PG), 1000㎎ of calcium(Oscal. Dong좀 pharmacy) and placebo were provided to CG and PG, respectively for 10 months. Nutrient intake, hematological iron status and proportion of anemia were evaluated before and after supplementation. Calcium supplementation significantly increased calcium intake of CG from 305.3㎎ to 1514.6㎎. PG also showed significantly increased intake of calcium but the extent of increase was much lower(from 358.2㎎ to 535.1㎎). Mean RBC count, Hct, hemoglobin were not significantly changed for both CG and PG. Serum ferritin was significantly decreased from 50.0ng/㎖ to 41.2ng/㎖ for CG and from 60.2ng/㎖ to 30.8ng/㎖ for PG after supplementation. The proportion of anemic female estimated with hemoglobin level was elevated from 3.4% to 37.9 for CG and from 7.7% to 42.3% for PG. Anemic female estimated with Hct was also increased for both CG and PG. The proportion of elderly female regarded as iron depleted estimated by serum ferritin(<15ng/㎖) was lowered from 31.0% to 20.7% for CG but increased from 0% to 19.2% for PG. It looks like calcium supplementation in the form capsule did not cause adverse effect more than placebo.