Lorazepam제제(製劑)의 용출속도(溶出速度)에 미치는 인자(因子)

Some Factors Influencing the Dissolution Rate of Lorazepam Formulations

The effect of diluents and lubricants on the dissolution rate of lorazepam was studied. The results were as following. 1. An average order of dissolution rate can be stated as; lactose> avicel> starch> kaolin. 2. The effects of lubicants is not significant generally but in the case of starch the dissolution rate is greatly effected by magnesium stearate.

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