한국산 생약으로부터 해독물질의 개발(제2보) 흰쥐 간장내의 카드뮴 축적에 미치는 금은화 추출물의 영향

Development of Antitoxic Agents from Korean Medicinal Plants. Part 2. Effects of Lonicerae flos Extract on the Accumulation of Cadmium in Liver

This study was conducted to investigate the metallothionein (MT) induction by Lonicerae rios in cadmium chloride intoxication. The results were as follows: Generally, detoxication effects by Lonicerae fios extract increased to the increase of extract concentrations. When 90 mg/kg dosage of Lonicerae fios extract was administered, it showed the highest antitoxic effects in metallothionein induction. From the above results, Lonicerae rios extract increased metallothionein concentration and decreased the toxicity of cadmium in liver.

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