극지미생물 Arthrobacter sp. PAMC 25486의 돌연변이유발 물질에 대한 감수성 평가

Investigation of the Susceptibility of Arctic Arthrobacter sp. PAMC 25486 to Mutagens

This study was conducted to investigate the sensitivity of Arthrobacter sp. PAMC 25486to various mutagens. γ-ray, UV-ray, Ethyl methane sulfonate (EMS) and hydrogen peroxide (H2O2)were used as mutagen, and the survival rate of Arthrobacter sp. was measured at various doses ofγ-ray and UV-ray, and concentrations of EMS and H2O2. Decimal reduction dose (D10 value) ofArthrobacter sp. was determined 370 Gy for a gamma irradiation treatment, 0.019 J for a UV ray,2.5 mM for EMS, and 230 mM for H2O2. This result will be applied for the development of superiormutant strain of Arctic bacteria producing valuable compounds.

This study was conducted to investigate the sensitivity of Arthrobacter sp. PAMC 25486to various mutagens. γ-ray, UV-ray, Ethyl methane sulfonate (EMS) and hydrogen peroxide (H2O2)were used as mutagen, and the survival rate of Arthrobacter sp. was measured at various doses ofγ-ray and UV-ray, and concentrations of EMS and H2O2. Decimal reduction dose (D10 value) ofArthrobacter sp. was determined 370 Gy for a gamma irradiation treatment, 0.019 J for a UV ray,2.5 mM for EMS, and 230 mM for H2O2. This result will be applied for the development of superiormutant strain of Arctic bacteria producing valuable compounds.