The purpose of this study is to examine the effects of acute exhaustive exercise on serum BDNF, IGF-1 levels and cognitive function. As study subjects, 16 healthy male college students were selected, and each 8 male college students were assigned to exercise group and control group randomly. In this study, exercise group was carried out treadmill running until all-out and exercise time to exhaustion was recorded. Blood samples were collected two times at pre-test and post-test for the analyses of serum brain-derived neurotrophic factor(BDNF) and insulin-like growth factor-1(IGF-1). Also, Stroop color-word test performed at same times as blood sampling. The results of the study showed that the concentrations of serum BDNF, IGF-1, and Stroop color-word test scores were significantly increased after acute exhaustive exercise(p<.05). BDNF and Stroop color-word test scores were significantly higher at post-test in exercise group compared to in control group(p<.05). It was also found that there are significant correlations between the changes of serum BDNF and IGF-1(p<.05). These results suggest that acute exhaustive exercise has positive effects on cognitive functions by increasing the BDNF.
The purpose of this study is to examine the effects of acute exhaustive exercise on serum BDNF, IGF-1 levels and cognitive function. As study subjects, 16 healthy male college students were selected, and each 8 male college students were assigned to exercise group and control group randomly. In this study, exercise group was carried out treadmill running until all-out and exercise time to exhaustion was recorded. Blood samples were collected two times at pre-test and post-test for the analyses of serum brain-derived neurotrophic factor(BDNF) and insulin-like growth factor-1(IGF-1). Also, Stroop color-word test performed at same times as blood sampling. The results of the study showed that the concentrations of serum BDNF, IGF-1, and Stroop color-word test scores were significantly increased after acute exhaustive exercise(p<.05). BDNF and Stroop color-word test scores were significantly higher at post-test in exercise group compared to in control group(p<.05). It was also found that there are significant correlations between the changes of serum BDNF and IGF-1(p<.05). These results suggest that acute exhaustive exercise has positive effects on cognitive functions by increasing the BDNF.
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