promotion program using MBTI on self-esteem, depression, and anger of the high school students. Methods: Data was collected from 27 students who were interested with MBTI program at an high school students in D city from October 20, 2014 to December 03, 2014. The collected data were analyzed by frequency, percentage, and paired t-test, with the SPSS/WIN 18.0 program. Results: After participating in the peer relationship promotion program using MBTI, the mean score of differences with depression, self-esteem, and and anger in high school students was 6.0, 2.8, 2.6 respectively. significant differences were found between pre and post-test in self-esteem(t=-3.19, p=.004) and depression(t=3.50, p=.002). However, there was no significant difference in anger. Conclusion: The results suggest that the peer relationship promotion program using MBTI can reduce high school students’s depression by helping them to enhance their self-esteem. Furthermore, MBTI is an effective nursing intervention to improve students’ peer relationship.