양성 정신분열증과 음성 정신분열증

Positive and Negative Schizophrenia

This purpose of this study was to infer the cause of cognitive difference between positive schizophrenia and negative schizophrenia. Previous course of the illness, family history of mental illness, and Ventricle-Brain Ratio(VBR) as well as cognitive function were investigated. 57 schizophrenics were subdivided into 2 subtypes (positive ; 30，negative ; 27) for comparison. The results were as follows • 1) The duration of illness was significantly longer in negative schizophrenia than in positive schizophrenia. 2) There were no significant difference in mean age, age of onset, number and duration of hospitalization, and family history of mental illness. 3) No significant differene was found between negative schizophrenia and positive schizophrenia in terms of Ventricle-Brain Ratio(VBR). 4) The scores of Brief Psychiatric Rating Scale (BPRS) for psychotic symptoms at admission and at 4 week later were significantly higher in positive schizophrenia. Therapeutic responses rated by BPRS were significnatly prominent in both schizophrenia. 5) The score of Mini Mental Status Examination(MMSE) for evaluation of cognitive function was significantly lower in negative schizophrenia than in positive schizophrenia. 6) The score of Ventricle-Brain Ratio(VBR) was not closley related with that of Mini Mental Status Examination (MMSE) in each schizophrenia. 7) Judged from above results, it is suggested that the cognitive dysfunction found in negative schizophrenia is considered to be a fundamental phenomena rather than secondary phenomena